Estrogen-related receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Nuclear Hormone Receptors [1]) have yet to be officially paired with an endogenous ligand.

* Key recommended reading is highlighted with an asterisk

* Benoit G, Cooney A, Giguere V, Ingraham H, Lazar M, Muscat G, Perlmann T, Renaud JP, Schwabe J, Sladek F, Tsai MJ, Laudet V. (2006) International Union of Pharmacology. LXVI. Orphan nuclear receptors. Pharmacol. Rev., 58 (4): 798-836. [PMID:17132856]

Deblois G, Giguère V. (2011) Functional and physiological genomics of estrogen-related receptors (ERRs) in health and disease. Biochim. Biophys. Acta, 1812 (8): 1032-40. [PMID:21172432]

Deblois G, Giguère V. (2013) Oestrogen-related receptors in breast cancer: control of cellular metabolism and beyond. Nat. Rev. Cancer, 13 (1): 27-36. [PMID:23192231]

* Divekar SD, Tiek DM, Fernandez A, Riggins RB. (2016) Estrogen-related receptor β (ERRβ) - renaissance receptor or receptor renaissance?. Nucl Recept Signal, 14: e002. [PMID:27507929]

* Germain P, Staels B, Dacquet C, Spedding M, Laudet V. (2006) Overview of nomenclature of nuclear receptors. Pharmacol. Rev., 58 (4): 685-704. [PMID:17132848]

Gonzalez-Sanchez E, Firrincieli D, Housset C, Chignard N. (2015) Nuclear receptors in acute and chronic cholestasis. Dig Dis, 33 (3): 357-66. [PMID:26045270]

Huang P, Chandra V, Rastinejad F. (2010) Structural overview of the nuclear receptor superfamily: insights into physiology and therapeutics. Annu. Rev. Physiol., 72: 247-72. [PMID:20148675]

Hwang-Verslues WW, Sladek FM. (2010) HNF4α--role in drug metabolism and potential drug target?. Curr Opin Pharmacol, 10 (6): 698-705. [PMID:20833107]

Sladek FM. (2011) What are nuclear receptor ligands?. Mol. Cell. Endocrinol., 334 (1-2): 3-13. [PMID:20615454]

* Tam IS, Giguère V. (2016) There and back again: The journey of the estrogen-related receptors in the cancer realm. J. Steroid Biochem. Mol. Biol., 157: 13-9. [PMID:26151739]

* Wu D, Cheung A, Wang Y, Yu S, Chan FL. (2016) The emerging roles of orphan nuclear receptors in prostate cancer. Biochim. Biophys. Acta, 1866 (1): 23-36. [PMID:27264242]

1. Benoit G, Cooney A, Giguere V, Ingraham H, Lazar M, Muscat G, Perlmann T, Renaud JP, Schwabe J, Sladek F, Tsai MJ, Laudet V. (2006) International Union of Pharmacology. LXVI. Orphan nuclear receptors. Pharmacol. Rev., 58 (4): 798-836. [PMID:17132856]

2. Suetsugi M, Su L, Karlsberg K, Yuan YC, Chen S. (2003) Flavone and isoflavone phytoestrogens are agonists of estrogen-related receptors. Mol. Cancer Res., 1 (13): 981-91. [PMID:14638870]

3. Willy PJ, Murray IR, Qian J, Busch BB, Stevens WC, Martin R, Mohan R, Zhou S, Ordentlich P, Wei P, Sapp DW, Horlick RA, Heyman RA, Schulman IG. (2004) Regulation of PPARgamma coactivator 1alpha (PGC-1alpha) signaling by an estrogen-related receptor alpha (ERRalpha) ligand. Proc. Natl. Acad. Sci. U.S.A., 101 (24): 8912-7. [PMID:15184675]

4. Yu DD, Forman BM. (2005) Identification of an agonist ligand for estrogen-related receptors ERRbeta/gamma. Bioorg. Med. Chem. Lett., 15 (5): 1311-3. [PMID:15713377]

5. Zuercher WJ, Gaillard S, Orband-Miller LA, Chao EY, Shearer BG, Jones DG, Miller AB, Collins JL, McDonnell DP, Willson TM. (2005) Identification and structure-activity relationship of phenolic acyl hydrazones as selective agonists for the estrogen-related orphan nuclear receptors ERRbeta and ERRgamma. J. Med. Chem., 48 (9): 3107-9. [PMID:15857113]