Opsin receptors | G protein-coupled receptors | IUPHAR/BPS Guide to PHARMACOLOGY

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Opsin receptors C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Receptors

OPN1LW Show summary »« Hide summary More detailed page go icon to follow link

Target Id	2961
Nomenclature	OPN1LW
Previous and unofficial names	psin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan) \| opsin 1 (cone pigments) \| opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan)
Genes	OPN1LW (Hs), Opn1mw (Mm)
Ensembl ID	ENSG00000102076 (Hs), ENSMUSG00000031394 (Mm)
UniProtKB AC	P04000 (Hs), O35599 (Mm)
Principal transduction	-

OPN1MW Show summary »« Hide summary More detailed page go icon to follow link

Target Id	2962
Nomenclature	OPN1MW
Previous and unofficial names	opsin 1 (cone pigments), medium-wave-sensitive \| opsin 1 (cone pigments) \| opsin 1, medium wave sensitive \| opsin 1
Genes	OPN1MW (Hs), Opn1mw (Rn)
Ensembl ID	ENSG00000268221 (Hs), ENSRNOG00000051529 (Rn)
UniProtKB AC	P04001 (Hs), O35476 (Rn)
Principal transduction	-

OPN1SW Show summary »« Hide summary More detailed page go icon to follow link

Target Id	2960
Nomenclature	OPN1SW
Previous and unofficial names	opsin 1, short wave sensitive \| opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan) \| opsin 1 \| opsin 1 (cone pigments)
Genes	OPN1SW (Hs), Opn1sw (Mm), Opn1sw (Rn)
Ensembl ID	ENSG00000128617 (Hs), ENSMUSG00000058831 (Mm), ENSRNOG00000006874 (Rn)
UniProtKB AC	P03999 (Hs), P51491 (Mm), Q63652 (Rn)
Principal transduction	-

Rhodopsin Show summary »« Hide summary More detailed page go icon to follow link

OPN3 C Show summary »« Hide summary More detailed page go icon to follow link

OPN4 C Show summary »« Hide summary More detailed page go icon to follow link

OPN5 C Show summary »« Hide summary More detailed page go icon to follow link

Target Id	161
Nomenclature	OPN5
Previous and unofficial names	opsin 5 \| transmembrane protein 13 \| GPR136 \| PGR12 \| neuropsin \| PGR14 \| TMEM13 \| G protein-coupled receptor 136
Genes	OPN5 (Hs), Opn5 (Mm), Opn5 (Rn)
Ensembl ID	ENSG00000124818 (Hs), ENSMUSG00000043972 (Mm), ENSRNOG00000012689 (Rn)
UniProtKB AC	Q6U736 (Hs), Q6VZZ7 (Mm), Q7TQN6 (Rn)
Principal transduction	G_i/G_o family
Comment	Evidence indicates that UV light triggers OPN5 to activate G_i-mediated signalling in mammalian tissues [1].

References

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How to cite this family page

Database page citation:

Opsin receptors. Accessed on 13/07/2025. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=975.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Christopoulos A, Davenport AP, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors. Br J Pharmacol. 180 Suppl 2:S23-S144.