2.3.2.27 RING-type E3 ubiquitin transferase

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2.3.2.- Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Enzymes

tripartite motif containing 21 Show summary »« Hide summary More detailed page go icon to follow link

Target Id

2967

Nomenclature

tripartite motif containing 21

Previous and unofficial names

RNF81 | RO52 | Ro/SSA | Sjogren syndrome antigen A1 | SSA1

Genes

TRIM21 (Hs), Trim21 (Mm), Trim21 (Rn)

Ensembl ID

ENSG00000132109 (Hs), ENSMUSG00000030966 (Mm), ENSRNOG00000018517 (Rn)

UniProtKB AC

P19474 (Hs), Q62191 (Mm)

EC number

2.3.2.27
Direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to acceptor protein. S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine <=> [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine

tripartite motif containing 38 / TRIM38 Show summary »« Hide summary More detailed page go icon to follow link

Target Id

2984

Nomenclature

tripartite motif containing 38

Systematic nomenclature

TRIM38

Previous and unofficial names

ring finger protein 15 | RNF15 | RORET | tripartite motif-containing 38

Genes

TRIM38 (Hs), Trim38 (Mm), Trim38 (Rn)

Ensembl ID

ENSG00000112343 (Hs), ENSMUSG00000064140 (Mm)

UniProtKB AC

O00635 (Hs)

EC number

2.3.2.27
Transfer of ubiquitin to L-lysine residue of the acceptor protein. S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine <=> [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine

How to cite this family page

Database page citation:

2.3.2.27 RING-type E3 ubiquitin transferase. Accessed on 13/07/2025. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=979.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.