CDK12 inhibitor 2 [Ligand Id: 10063] activity data from GtoPdb

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  • cyclin dependent kinase 12 in Human [GtoPdb: 1965] [UniProtKB: Q9NYV4]
  • This target only has 0 pki data point
1 _lig_chart_1 cyclin dependent kinase 12 Human
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  • cyclin dependent kinase 13 in Human [GtoPdb: 1966] [UniProtKB: Q14004]
  • This target only has 0 pki data point
2 _lig_chart_2 cyclin dependent kinase 13 Human
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  • cyclin dependent kinase 7 in Human [GtoPdb: 1979] [UniProtKB: P50613]
  • This target only has 0 pki data point
3 _lig_chart_3 cyclin dependent kinase 7 Human
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  • cyclin dependent kinase 8 in Human [GtoPdb: 1980] [UniProtKB: P49336]
  • This target only has 0 pki data point
4 _lig_chart_4 cyclin dependent kinase 8 Human
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  • cyclin dependent kinase 9 in Human [GtoPdb: 1981] [UniProtKB: P50750]
  • This target only has 0 pki data point
5 _lig_chart_5 cyclin dependent kinase 9 Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
cyclin dependent kinase 12 in Human [GtoPdb: 1965] [UniProtKB: Q9NYV4]
GtoPdb - - 7.28 pIC50 52 nM IC50 J. Med. Chem. (2018) 61: 7710-7728 [PMID:30067358]
cyclin dependent kinase 13 in Human [GtoPdb: 1966] [UniProtKB: Q14004]
GtoPdb - - 8 pIC50 10 nM IC50 J. Med. Chem. (2018) 61: 7710-7728 [PMID:30067358]
cyclin dependent kinase 7 in Human [GtoPdb: 1979] [UniProtKB: P50613]
GtoPdb - - 5 pIC50 >10000 nM IC50 J. Med. Chem. (2018) 61: 7710-7728 [PMID:30067358]
cyclin dependent kinase 8 in Human [GtoPdb: 1980] [UniProtKB: P49336]
GtoPdb - - 5 pIC50 >10000 nM IC50 J. Med. Chem. (2018) 61: 7710-7728 [PMID:30067358]
cyclin dependent kinase 9 in Human [GtoPdb: 1981] [UniProtKB: P50750]
GtoPdb - - 4.8 pIC50 16000 nM IC50 J. Med. Chem. (2018) 61: 7710-7728 [PMID:30067358]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.