[125I]IRL1620 [Ligand Id: 1007] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL3188091 (Irl-1620, IRL-1620, PMZ-1620, Sovatelitide, Sovateltide, Spi 1620, Spi-1620, SPI 1620, SPI-1620)
  • ETB receptor in Human [GtoPdb: 220] [UniProtKB: P24530]
  • ETB receptor in Rat [GtoPdb: 220] [UniProtKB: P21451]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
ETB receptor in Human [GtoPdb: 220] [UniProtKB: P24530]
GtoPdb - - 10.1 pKd 0.08 nM Kd J Pharmacol Exp Ther (1994) 268: 202-7 [PMID:8301559]
ETB receptor in Rat [GtoPdb: 220] [UniProtKB: P21451]
GtoPdb - - 10.1 pKd - - - J Pharmacol Exp Ther (1994) 268: 202-7 [PMID:8301559]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]