dual BRD4/PLK1 inhibitor 23 [Ligand Id: 10072] activity data from GtoPdb

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  • bromodomain containing 4 in Human [GtoPdb: 1945] [UniProtKB: O60885]
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  • polo like kinase 1 in Human [GtoPdb: 2168] [UniProtKB: P53350]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
bromodomain containing 4 in Human [GtoPdb: 1945] [UniProtKB: O60885]
GtoPdb Biochemical inhibition of BRD4-BD1. - 7.55 pIC50 28 nM IC50 J. Med. Chem. (2018) 61: 7785-7795 [PMID:30125504]
polo like kinase 1 in Human [GtoPdb: 2168] [UniProtKB: P53350]
GtoPdb Biochemical inhibition of PLK1. - 7.4 pIC50 40 nM IC50 J. Med. Chem. (2018) 61: 7785-7795 [PMID:30125504]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.