RO3306 [Ligand Id: 10095] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| cyclin dependent kinase 1 in Human [GtoPdb: 1961] [UniProtKB: P06493] | ||||||||
| GtoPdb | In vitro inhibition of human CDK1/cyclin B. | - | 7.33 | pIC50 | 47 | nM | IC50 | J Med Chem (2018) 61: 9105-9120 [PMID:30234987] |
| cyclin dependent kinase 2 in Human [GtoPdb: 1973] [UniProtKB: P24941] | ||||||||
| GtoPdb | In vitro inhibition of human CDK2/cyclin A. | - | 6.6 | pIC50 | 253 | nM | IC50 | J Med Chem (2018) 61: 9105-9120 [PMID:30234987] |
| GtoPdb | In vitro inhibition of human CDK2/cyclin E. | - | 6.73 | pIC50 | 186 | nM | IC50 | J Med Chem (2018) 61: 9105-9120 [PMID:30234987] |
| cyclin dependent kinase 5 in Human [GtoPdb: 1977] [UniProtKB: Q00535] | ||||||||
| GtoPdb | In vitro inhibition of human CDK5/p25. | - | 5.61 | pIC50 | 2480 | nM | IC50 | J Med Chem (2018) 61: 9105-9120 [PMID:30234987] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
