acalisib [Ligand Id: 10096] activity data from GtoPdb

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  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha in Human [GtoPdb: 2153] [UniProtKB: P42336]
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  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta in Human [GtoPdb: 2154] [UniProtKB: P42338]
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  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta in Human [GtoPdb: 2155] [UniProtKB: O00329]
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  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma in Human [GtoPdb: 2156] [UniProtKB: P48736]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha in Human [GtoPdb: 2153] [UniProtKB: P42336]
GtoPdb In an in vitro biochemical assay using recombinant enzyme. - 5.26 pIC50 5441 nM IC50 J. Biol. Chem. (2013) 288: 35346-57 [PMID:24133210]
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta in Human [GtoPdb: 2154] [UniProtKB: P42338]
GtoPdb In an in vitro biochemical assay using recombinant enzyme. - 5.47 pIC50 3377 nM IC50 J. Biol. Chem. (2013) 288: 35346-57 [PMID:24133210]
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta in Human [GtoPdb: 2155] [UniProtKB: O00329]
GtoPdb In an in vitro biochemical assay using recombinant enzyme. - 7.9 pIC50 12.7 nM IC50 J. Biol. Chem. (2013) 288: 35346-57 [PMID:24133210]
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma in Human [GtoPdb: 2156] [UniProtKB: P48736]
GtoPdb In an in vitro biochemical assay using recombinant enzyme. - 5.86 pIC50 1389 nM IC50 J. Biol. Chem. (2013) 288: 35346-57 [PMID:24133210]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.