AM1710 [Ligand Id: 10202] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL266712 (AM-1710) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| CB1 receptor/Cannabinoid CB1 receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3571] [GtoPdb: 56] [UniProtKB: P20272] | ||||||||
| GtoPdb | - | - | 6.44 | pKi | 360 | nM | Ki | J Med Chem (2007) 50: 6493-500 [PMID:18038967] |
| ChEMBL | Displacement of [3H]CP-55940 from CB1 receptor in rat brain synaptosomes | B | 6.44 | pKi | 360 | nM | Ki | J Med Chem (2007) 50: 6493-6500 [PMID:18038967] |
| CB2 receptor/Cannabinoid CB2 receptor in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5373] [GtoPdb: 57] [UniProtKB: P47936] | ||||||||
| GtoPdb | - | - | 8.17 | pKi | 6.7 | nM | Ki | J Med Chem (2007) 50: 6493-500 [PMID:18038967] |
| ChEMBL | Displacement of [3H]CP-55940 from CB2 receptor in mouse spleen membranes | B | 8.17 | pKi | 6.7 | nM | Ki | J Med Chem (2007) 50: 6493-6500 [PMID:18038967] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
