AM1710 [Ligand Id: 10202] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL266712 (AM-1710)
  • CB1 receptor/Cannabinoid CB1 receptor in Rat [ChEMBL: CHEMBL3571] [GtoPdb: 56] [UniProtKB: P20272]
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  • CB2 receptor/Cannabinoid CB2 receptor in Mouse [ChEMBL: CHEMBL5373] [GtoPdb: 57] [UniProtKB: P47936]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
CB1 receptor/Cannabinoid CB1 receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3571] [GtoPdb: 56] [UniProtKB: P20272]
GtoPdb - - 6.44 pKi 360 nM Ki J Med Chem (2007) 50: 6493-500 [PMID:18038967]
ChEMBL Displacement of [3H]CP-55940 from CB1 receptor in rat brain synaptosomes B 6.44 pKi 360 nM Ki J. Med. Chem. (2007) 50: 6493-6500 [PMID:18038967]
CB2 receptor/Cannabinoid CB2 receptor in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5373] [GtoPdb: 57] [UniProtKB: P47936]
GtoPdb - - 8.17 pKi 6.7 nM Ki J Med Chem (2007) 50: 6493-500 [PMID:18038967]
ChEMBL Displacement of [3H]CP-55940 from CB2 receptor in mouse spleen membranes B 8.17 pKi 6.7 nM Ki J. Med. Chem. (2007) 50: 6493-6500 [PMID:18038967]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]