LUF7602 [Ligand Id: 10351] activity data from GtoPdb

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  • A1 receptor in Human [GtoPdb: 18] [UniProtKB: P30542]
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  • A2A receptor in Human [GtoPdb: 19] [UniProtKB: P29274]
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  • A3 receptor in Human [GtoPdb: 21] [UniProtKB: P0DMS8]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
A1 receptor in Human [GtoPdb: 18] [UniProtKB: P30542]
GtoPdb Affinity determined from the displacement of specific [3H]DPCPX binding on CHO cell membranes stably expressing human adenosine A1 receptors at 25 °C during 2 h of incubation. - 6.1 pKi 794 nM Ki J. Med. Chem. (2019) 62: 3539-3552 [PMID:30869893]
A2A receptor in Human [GtoPdb: 19] [UniProtKB: P29274]
GtoPdb Affinity determined from the displacement of specific [3H]ZM241385 binding on HEK293 cell membranes stably expressing human adenosine A2A receptors at 25 °C during 2 h of incubation. - 5.9 pKi 1259 nM Ki J. Med. Chem. (2019) 62: 3539-3552 [PMID:30869893]
A3 receptor in Human [GtoPdb: 21] [UniProtKB: P0DMS8]
GtoPdb Displacement of [3H]PSB-11 binding from the hA3AR (in membranes from stably transfected CHO cells) following preincubation for 4 h, - 8 pKi 10 nM Ki J. Med. Chem. (2019) 62: 3539-3552 [PMID:30869893]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.