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1
_lig_chart_1
Nav1.1
Human
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2
_lig_chart_2
Nav1.2
Human
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3
_lig_chart_3
Nav1.3
Human
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4
_lig_chart_4
Nav1.4
Human
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5
_lig_chart_5
Nav1.5
Human
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6
_lig_chart_6
Nav1.6
Human
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
---|---|---|---|---|---|---|---|---|
Nav1.1 in Human [GtoPdb: 578] [UniProtKB: P35498] | ||||||||
GtoPdb | Kd determined in a Dynaflow Manual Patch Clamp experiment. | - | 6 | pKd | >1000 | nM | Kd | J. Med. Chem. (2019) 62: 4091-4109 [PMID:30943032] |
Nav1.2 in Human [GtoPdb: 579] [UniProtKB: Q99250] | ||||||||
GtoPdb | Kd determined in a Dynaflow Manual Patch Clamp experiment. | - | 7.92 | pKd | 12 | nM | Kd | J. Med. Chem. (2019) 62: 4091-4109 [PMID:30943032] |
Nav1.3 in Human [GtoPdb: 580] [UniProtKB: Q9NY46] | ||||||||
GtoPdb | Kd determined in a Dynaflow Manual Patch Clamp experiment. | - | 6 | pKd | >1000 | nM | Kd | J. Med. Chem. (2019) 62: 4091-4109 [PMID:30943032] |
Nav1.4 in Human [GtoPdb: 581] [UniProtKB: P35499] | ||||||||
GtoPdb | Kd determined in a Dynaflow Manual Patch Clamp experiment. | - | 6 | pKd | >1000 | nM | Kd | J. Med. Chem. (2019) 62: 4091-4109 [PMID:30943032] |
Nav1.5 in Human [GtoPdb: 582] [UniProtKB: Q14524] | ||||||||
GtoPdb | Kd determined in a Dynaflow Manual Patch Clamp experiment. | - | 6 | pKd | >1000 | nM | Kd | J. Med. Chem. (2019) 62: 4091-4109 [PMID:30943032] |
Nav1.6 in Human [GtoPdb: 583] [UniProtKB: Q9UQD0] | ||||||||
GtoPdb | Kd determined in a Dynaflow Manual Patch Clamp experiment. | - | 7.54 | pKd | 29 | nM | Kd | J. Med. Chem. (2019) 62: 4091-4109 [PMID:30943032] |
Nav1.7 in Human [GtoPdb: 584] [UniProtKB: Q15858] | ||||||||
GtoPdb | Kd determined in a Dynaflow Manual Patch Clamp experiment. | - | 9.42 | pKd | 0.38 | nM | Kd | J. Med. Chem. (2019) 62: 4091-4109 [PMID:30943032] |
GtoPdb | Binding affinity for hNav1.7 determined in a radioligand binding assay. | - | 9.1 | pKi | 0.79 | nM | Ki | J. Med. Chem. (2019) 62: 4091-4109 [PMID:30943032] |
Nav1.7 in Rat [GtoPdb: 584] [UniProtKB: O08562] | ||||||||
GtoPdb | Kd determined in a Dynaflow Manual Patch Clamp experiment. | - | 7.48 | pKd | 33 | nM | Kd | J. Med. Chem. (2019) 62: 4091-4109 [PMID:30943032] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.