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ChEMBL ligand: CHEMBL3989220 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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Plasmodium falciparum lysyl-tRNA synthetase in Plasmodium falciparum K1 [GtoPdb: 3059] | ||||||||
GtoPdb | Parasite growth inhibition assay | - | 6.29 | pEC50 | 510 | nM | EC50 | Proc Natl Acad Sci USA (2019) 116: 7015-7020 [PMID:30894487] |
Plasmodium falciparum lysyl-tRNA synthetase in Plasmodium falciparum NF54 [GtoPdb: 3059] | ||||||||
GtoPdb | Parasite stage V gametocyte assay | - | 5 | pEC50 | 9900 | nM | EC50 | Proc Natl Acad Sci USA (2019) 116: 7015-7020 [PMID:30894487] |
GtoPdb | Parasite gamete formation assay | - | 6 | pEC50 | >1000 | nM | EC50 | Proc Natl Acad Sci USA (2019) 116: 7015-7020 [PMID:30894487] |
GtoPdb | Parasite growth inhibition assay | - | 6.41 | pEC50 | 390 | nM | EC50 | Proc Natl Acad Sci USA (2019) 116: 7015-7020 [PMID:30894487] |
Plasmodium falciparum lysyl-tRNA synthetase in Plasmodium vivax [GtoPdb: 3059] | ||||||||
GtoPdb | Parasite liver stage assay | - | 6.02 | pEC50 | 950 | nM | EC50 | Proc Natl Acad Sci USA (2019) 116: 7015-7020 [PMID:30894487] |
Plasmodium falciparum lysyl-tRNA synthetase in Plasmodium falciparum 3D7 [GtoPdb: 3059] [UniProtKB: Q8IDJ8] | ||||||||
GtoPdb | Parasite growth inhibition assay | - | 6.57 | pEC50 | 270 | nM | EC50 | Proc Natl Acad Sci USA (2019) 116: 7015-7020 [PMID:30894487] |
ChEMBL data shown on this page come from version 28:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]