BAY-8002 [Ligand Id: 10405] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Monocarboxylate transporter 1 in Human [GtoPdb: 988] [UniProtKB: P53985] | ||||||||
| GtoPdb | Inhibition of [3H]-BAY-8002 binding to membranes prepared from human MCT1-expressing DLD-1 cells. | - | 8.3 | pKi | 5.02 | nM | Ki | Mol Cancer Ther (2018) 17: 2285-2296 [PMID:30115664] |
| GtoPdb | Inhibition of lactate transport in X. laevis oocytes expressing hMCT1. | - | 9 | pIC50 | 1 | nM | IC50 | Mol Cancer Ther (2018) 17: 2285-2296 [PMID:30115664] |
| Monocarboxylate transporter 2 in Human [GtoPdb: 990] [UniProtKB: O60669] | ||||||||
| GtoPdb | Inhibition of lactate transport in X. laevis oocytes expressing hMCT2. | - | 8.3 | pIC50 | 5 | nM | IC50 | Mol Cancer Ther (2018) 17: 2285-2296 [PMID:30115664] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
