CHMFL-KIT-64 [Ligand Id: 10420] activity data from GtoPdb

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  • platelet derived growth factor receptor alpha in Human [GtoPdb: 1803] [UniProtKB: P16234]
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  • platelet derived growth factor receptor beta in Human [GtoPdb: 1804] [UniProtKB: P09619]
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  • KIT proto-oncogene, receptor tyrosine kinase in Human [GtoPdb: 1805] [UniProtKB: P10721]
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  • colony stimulating factor 1 receptor in Human [GtoPdb: 1806] [UniProtKB: P07333]
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  • fms related receptor tyrosine kinase 4 in Human [GtoPdb: 1814] [UniProtKB: P35916]
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  • discoidin domain receptor tyrosine kinase 1 in Human [GtoPdb: 1843] [UniProtKB: Q08345]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
platelet derived growth factor receptor alpha in Human [GtoPdb: 1803] [UniProtKB: P16234]
GtoPdb In a biochemical assay. - 7.6 pIC50 25 nM IC50 J Med Chem (2019) 62: 6083-6101 [PMID:31250638]
platelet derived growth factor receptor beta in Human [GtoPdb: 1804] [UniProtKB: P09619]
GtoPdb In a biochemical assay. - 7.01 pIC50 97 nM IC50 J Med Chem (2019) 62: 6083-6101 [PMID:31250638]
KIT proto-oncogene, receptor tyrosine kinase in Human [GtoPdb: 1805] [UniProtKB: P10721]
GtoPdb In a biochemical assay. - 8.4 pIC50 4 nM IC50 J Med Chem (2019) 62: 6083-6101 [PMID:31250638]
colony stimulating factor 1 receptor in Human [GtoPdb: 1806] [UniProtKB: P07333]
GtoPdb In a biochemical assay. - 7.74 pIC50 18 nM IC50 J Med Chem (2019) 62: 6083-6101 [PMID:31250638]
fms related receptor tyrosine kinase 4 in Human [GtoPdb: 1814] [UniProtKB: P35916]
GtoPdb In a biochemical assay. - 6.92 pIC50 121 nM IC50 J Med Chem (2019) 62: 6083-6101 [PMID:31250638]
discoidin domain receptor tyrosine kinase 1 in Human [GtoPdb: 1843] [UniProtKB: Q08345]
GtoPdb In a biochemical assay. - 6.87 pIC50 135 nM IC50 J Med Chem (2019) 62: 6083-6101 [PMID:31250638]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.