compound 5d [PMID: 31335136] [Ligand Id: 10441] activity data from GtoPdb

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  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha in Human [GtoPdb: 2153] [UniProtKB: P42336]
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  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta in Human [GtoPdb: 2154] [UniProtKB: P42338]
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  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta in Human [GtoPdb: 2155] [UniProtKB: O00329]
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  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma in Human [GtoPdb: 2156] [UniProtKB: P48736]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha in Human [GtoPdb: 2153] [UniProtKB: P42336]
GtoPdb - - 9.06 pIC50 0.87 nM IC50 J. Med. Chem. (2019) 62: 8873-8879 [PMID:31335136]
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta in Human [GtoPdb: 2154] [UniProtKB: P42338]
GtoPdb - - 9.15 pIC50 0.7 nM IC50 J. Med. Chem. (2019) 62: 8873-8879 [PMID:31335136]
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta in Human [GtoPdb: 2155] [UniProtKB: O00329]
GtoPdb - - 8.96 pIC50 1.1 nM IC50 J. Med. Chem. (2019) 62: 8873-8879 [PMID:31335136]
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma in Human [GtoPdb: 2156] [UniProtKB: P48736]
GtoPdb - - 8.8 pIC50 1.6 nM IC50 J. Med. Chem. (2019) 62: 8873-8879 [PMID:31335136]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.