brepocitinib [Ligand Id: 10459] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Janus kinase 1 in Human [GtoPdb: 2047] [UniProtKB: P23458] | ||||||||
| GtoPdb | - | - | 7.77 | pIC50 | 17 | nM | IC50 | J Med Chem (2018) 61: 8597-8612 [PMID:30113844] |
| Janus kinase 2 in Human [GtoPdb: 2048] [UniProtKB: O60674] | ||||||||
| GtoPdb | - | - | 7.11 | pIC50 | 77 | nM | IC50 | J Med Chem (2018) 61: 8597-8612 [PMID:30113844] |
| Janus kinase 3 in Human [GtoPdb: 2049] [UniProtKB: P52333] | ||||||||
| GtoPdb | - | - | 5.19 | pIC50 | 6494 | nM | IC50 | J Med Chem (2018) 61: 8597-8612 [PMID:30113844] |
| tyrosine kinase 2 in Human [GtoPdb: 2269] [UniProtKB: P29597] | ||||||||
| GtoPdb | - | - | 7.64 | pIC50 | 23 | nM | IC50 | J Med Chem (2018) 61: 8597-8612 [PMID:30113844] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
