compound 16 [PMID: 31498617] [Ligand Id: 10482] activity data from GtoPdb

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  • MRGPRX1 in Human [GtoPdb: 156] [UniProtKB: Q96LB2]
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  • δ receptor in Human [GtoPdb: 317] [UniProtKB: P41143]
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  • κ receptor in Human [GtoPdb: 318] [UniProtKB: P41145]
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  • μ receptor in Human [GtoPdb: 319] [UniProtKB: P35372]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
MRGPRX1 in Human [GtoPdb: 156] [UniProtKB: Q96LB2]
GtoPdb Agonist activity at human MRGPRX1 stably expressed in HEK293 cells by FLIPR claciun mobilisation assay. - 7.3 pEC50 50 nM EC50 J. Med. Chem. (2019) 62: 8631-8641 [PMID:31498617]
δ receptor in Human [GtoPdb: 317] [UniProtKB: P41143]
GtoPdb Receptor binding in a radioligand displacement assay using [3H]DADLE as tracer. - 5.61 pKi 2470 nM Ki J. Med. Chem. (2019) 62: 8631-8641 [PMID:31498617]
κ receptor in Human [GtoPdb: 318] [UniProtKB: P41145]
GtoPdb Receptor binding in a radioligand displacement assay using [3H]U-69,593 as tracer. - 4.92 pKi 12100 nM Ki J. Med. Chem. (2019) 62: 8631-8641 [PMID:31498617]
μ receptor in Human [GtoPdb: 319] [UniProtKB: P35372]
GtoPdb Receptor binding in a radioligand displacement assay using [3H]DAMGO as tracer. - 5.43 pKi 3730 nM Ki J. Med. Chem. (2019) 62: 8631-8641 [PMID:31498617]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.