SWE101 [Ligand Id: 10494] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| COX-1 in Human [GtoPdb: 1375] [UniProtKB: P23219] | ||||||||
| GtoPdb | - | - | 5.92 | pIC50 | 1200 | nM | IC50 | J Med Chem (2019) 62: 8443-8460 [PMID:31436984] |
| COX-2 in Human [GtoPdb: 1376] [UniProtKB: P35354] | ||||||||
| GtoPdb | - | - | 6.38 | pIC50 | 420 | nM | IC50 | J Med Chem (2019) 62: 8443-8460 [PMID:31436984] |
| epoxide hydrolase 2 in Human [GtoPdb: 2970] [UniProtKB: P34913] | ||||||||
| GtoPdb | Binding affinity for the N-terminal domain of sEH by isothermal titration calorimetry. | - | 6.52 | pKd | 300 | nM | Kd | J Med Chem (2019) 62: 8443-8460 [PMID:31436984] |
| GtoPdb | Inhibition of sEH's phosphatase activity. | - | 7.24 | pIC50 | 58 | nM | IC50 | J Med Chem (2019) 62: 8443-8460 [PMID:31436984] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
