OMO-1 [Ligand Id: 10507] activity data from GtoPdb

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

  • MET proto-oncogene, receptor tyrosine kinase in Human [GtoPdb: 1815] [UniProtKB: P08581]
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
MET proto-oncogene, receptor tyrosine kinase in Human [GtoPdb: 1815] [UniProtKB: P08581]
GtoPdb Inhibition of HGF stimulated c-Met phosphorylation in a cell-based assay. - 7.92 pIC50 12 nM IC50 WO2007075567A1. Triazolopyridazines as tyrosine kinase modulators (2007)
GtoPdb Inhibition of c-Met autophosphorylation measured in a time resolved fluorescence assay (DELFIA). - 9 pIC50 1 nM IC50 WO2007075567A1. Triazolopyridazines as tyrosine kinase modulators (2007)

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.