ChEMBL ligand: CHEMBL63829 (3,3,14,14-Tetramethylhexadecanedioic Acid, 3,3,14,14-Tetramethyl-Hexadecanedioic Acid)
ATP-citrate synthase in Rat [ChEMBL: CHEMBL2745] [UniProtKB: P16638] There should be some charts here, you may need to enable JavaScript!
FFA1 receptor in Human [GtoPdb: 225] [UniProtKB: O14842] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
ATP-citrate synthase in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2745] [UniProtKB: P16638]
ChEMBL	Inhibition against ATP-citrate lyase in liver.	B	1.8	pKi	16000000	nM	Ki	J Med Chem (1989) 32: 2072-2084 [PMID:2788743]
ChEMBL	Competitive inhibition of rat liver ACLY using citrate as substrate by spectrophotometric analysis	B	4.8	pKi	16000	nM	Ki	J Med Chem (2011) 54: 5615-5638 [PMID:21726077]
ChEMBL	Inhibition of rat liver ACLY	B	4.8	pKi	16000	nM	Ki	Eur J Med Chem (2018) 157: 1276-1291 [PMID:30195238]
ChEMBL	Competitive inhibition of rat liver ACLY using CoA as substrate by spectrophotometric analysis	B	5.52	pKi	3000	nM	Ki	J Med Chem (2011) 54: 5615-5638 [PMID:21726077]
FFA1 receptor in Human [GtoPdb: 225] [UniProtKB: O14842]
GtoPdb	-	-	5.9	pEC50	-	-	-	Biochem Biophys Res Commun (2003) 301: 406-10 [PMID:12565875]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]