THAL-SNS-032 [Ligand Id: 10547] activity data from GtoPdb

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  • cyclin dependent kinase 1 in Human [GtoPdb: 1961] [UniProtKB: P06493]
  • This target only has 0 pki data point
1 _lig_chart_1 cyclin dependent kinase 1 Human
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  • cyclin dependent kinase 2 in Human [GtoPdb: 1973] [UniProtKB: P24941]
  • This target only has 0 pki data point
2 _lig_chart_2 cyclin dependent kinase 2 Human
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  • cyclin dependent kinase 7 in Human [GtoPdb: 1979] [UniProtKB: P50613]
  • This target only has 0 pki data point
3 _lig_chart_3 cyclin dependent kinase 7 Human
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  • cyclin dependent kinase 9 in Human [GtoPdb: 1981] [UniProtKB: P50750]
  • This target only has 0 pki data point
4 _lig_chart_4 cyclin dependent kinase 9 Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
cyclin dependent kinase 1 in Human [GtoPdb: 1961] [UniProtKB: P06493]
GtoPdb Biochemical inhibition of CDK1/CycB. - 6.77 pIC50 171 nM IC50 Nat. Chem. Biol. (2018) 14: 163-170 [PMID:29251720]
cyclin dependent kinase 2 in Human [GtoPdb: 1973] [UniProtKB: P24941]
GtoPdb Biochemical inhibition of CDK2/cyclin A - 7.21 pIC50 62 nM IC50 Nat. Chem. Biol. (2018) 14: 163-170 [PMID:29251720]
cyclin dependent kinase 7 in Human [GtoPdb: 1979] [UniProtKB: P50613]
GtoPdb Inhibition of CDK7/CycH/MNAT1. - 6.4 pIC50 398 nM IC50 Nat. Chem. Biol. (2018) 14: 163-170 [PMID:29251720]
cyclin dependent kinase 9 in Human [GtoPdb: 1981] [UniProtKB: P50750]
GtoPdb Biochemical inhibition of CDK9/CycT1. - 8.4 pIC50 4 nM IC50 Nat. Chem. Biol. (2018) 14: 163-170 [PMID:29251720]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.