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ChEMBL ligand: CHEMBL108778 (Isobutyric Acid) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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FFA3 receptor in Human [GtoPdb: 227] [UniProtKB: O14843] | ||||||||
GtoPdb | - | - | 4.8 | pEC50 | - | - | - |
J Biol Chem (2003) 278: 11312-9 [PMID:12496283]; Proc Natl Acad Sci USA (2004) 101: 1045-50 [PMID:14722361] |
FFA3 receptor/Free fatty acid receptor 3 in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3886125] [GtoPdb: 227] [UniProtKB: B2GV46] | ||||||||
ChEMBL | Agonist activity at rat GPR41 expressed in Saccharomyces cerevisiae MMY22 co-expressing chimeric Gpa1/Galpha0 by induction of FUSl-lacZ and FUS1-HIS3 reporter gene induction based pheromone response pathway coupled assay | B | 4.52 | pEC50 | 30000 | nM | EC50 | WO-2001061359-A2. Identification of modulators of GPR41 or GPR42 activity (2001) |
FFA2 receptor in Human [GtoPdb: 226] [UniProtKB: O15552] | ||||||||
GtoPdb | - | - | 3.8 | pEC50 | - | - | - | J Biol Chem (2003) 278: 25481-9 [PMID:12711604] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]