AZD7648 [Ligand Id: 10601] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha in Human [GtoPdb: 2153] [UniProtKB: P42336] | ||||||||
| GtoPdb | - | - | 7 | pIC50 | 100 | nM | IC50 | J Med Chem (2020) 63: 3461-3471 [PMID:31851518] |
| phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma in Human [GtoPdb: 2156] [UniProtKB: P48736] | ||||||||
| GtoPdb | - | - | 7.28 | pIC50 | 52 | nM | IC50 | J Med Chem (2020) 63: 3461-3471 [PMID:31851518] |
| protein kinase, DNA-activated, catalytic subunit in Human [GtoPdb: 2800] [UniProtKB: P78527] | ||||||||
| GtoPdb | Measuring inhibition of irradiation-induced DNA-PK autophosphorylation in A549 cells by ELISA. | - | 7.04 | pIC50 | 91 | nM | IC50 | J Med Chem (2020) 63: 3461-3471 [PMID:31851518] |
| GtoPdb | Measured by time-resolved fluorescence (TR-FRET) in a biochemical assay. | - | 9.2 | pIC50 | 0.63 | nM | IC50 | J Med Chem (2020) 63: 3461-3471 [PMID:31851518] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
