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ChEMBL ligand: CHEMBL2440750 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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Rho associated coiled-coil containing protein kinase 2/Rho-associated protein kinase 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2973] [GtoPdb: 1504] [UniProtKB: O75116] | ||||||||
GtoPdb | - | - | 8.29 | pIC50 | 5.1 | nM | IC50 | Bioorg. Med. Chem. Lett. (2013) 23: 6442-6 [PMID:24119557] |
ChEMBL | Inhibition of ROCK2 (unknown origin) using long S6 kinase peptide as substrate by radiometric assay | B | 8.29 | pIC50 | 5.1 | nM | IC50 | Bioorg. Med. Chem. Lett. (2013) 23: 6442-6446 [PMID:24119557] |
ChEMBL data shown on this page come from version 27:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]