VBY-825 [Ligand Id: 10746] activity data from GtoPdb

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

  • cathepsin B in Human [GtoPdb: 2343] [UniProtKB: P07858]
There should be some charts here, you may need to enable JavaScript!
  • cathepsin F in Human [GtoPdb: 2347] [UniProtKB: Q9UBX1]
There should be some charts here, you may need to enable JavaScript!
  • cathepsin L in Human [GtoPdb: 2351] [UniProtKB: P07711]
There should be some charts here, you may need to enable JavaScript!
  • cathepsin V in Human [GtoPdb: 2352] [UniProtKB: O60911]
There should be some charts here, you may need to enable JavaScript!
  • cathepsin S in Human [GtoPdb: 2353] [UniProtKB: P25774]
  • cathepsin S in Mouse [GtoPdb: 2353] [UniProtKB: O70370]
  • cathepsin S in Rat [GtoPdb: 2353] [UniProtKB: Q02765]
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
cathepsin B in Human [GtoPdb: 2343] [UniProtKB: P07858]
GtoPdb - - 9.48 pKi 0.33 nM Ki Biochimie (2010) 92: 1618-24 [PMID:20447439]
cathepsin F in Human [GtoPdb: 2347] [UniProtKB: Q9UBX1]
GtoPdb - - 8.33 pKi 4.7 nM Ki Biochimie (2010) 92: 1618-24 [PMID:20447439]
cathepsin L in Human [GtoPdb: 2351] [UniProtKB: P07711]
GtoPdb - - 9.6 pKi 0.25 nM Ki Biochimie (2010) 92: 1618-24 [PMID:20447439]
cathepsin V in Human [GtoPdb: 2352] [UniProtKB: O60911]
GtoPdb - - 9.6 pKi 0.25 nM Ki Biochimie (2010) 92: 1618-24 [PMID:20447439]
cathepsin S in Human [GtoPdb: 2353] [UniProtKB: P25774]
GtoPdb - - 9.89 pKi 0.13 nM Ki Biochimie (2010) 92: 1618-24 [PMID:20447439]
cathepsin S in Mouse [GtoPdb: 2353] [UniProtKB: O70370]
GtoPdb - - 10.4 pKi 0.04 nM Ki Biochimie (2010) 92: 1618-24 [PMID:20447439]
cathepsin S in Rat [GtoPdb: 2353] [UniProtKB: Q02765]
GtoPdb - - 9.11 pKi 0.77 nM Ki Biochimie (2010) 92: 1618-24 [PMID:20447439]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.