compound 3m [PMID: 32603117] [Ligand Id: 11099] activity data from GtoPdb

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  • phosphodiesterase 1C in Human [GtoPdb: 1296] [UniProtKB: Q14123]
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  • phosphodiesterase 4D in Human [GtoPdb: 1303] [UniProtKB: Q08499]
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  • phosphodiesterase 5A in Human [GtoPdb: 1304] [UniProtKB: O76074]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
phosphodiesterase 1C in Human [GtoPdb: 1296] [UniProtKB: Q14123]
GtoPdb Biochemical inhibition of recombinant PDE1C catalytic domain (aa147–531). - 8.54 pIC50 2.9 nM IC50 J Med Chem (2020) 63: 7867-7879 [PMID:32603117]
phosphodiesterase 4D in Human [GtoPdb: 1303] [UniProtKB: Q08499]
GtoPdb Biochemical inhibition of recombinant PDE4D2 catalytic domain (aa86–413). - 6.16 pIC50 699 nM IC50 J Med Chem (2020) 63: 7867-7879 [PMID:32603117]
phosphodiesterase 5A in Human [GtoPdb: 1304] [UniProtKB: O76074]
GtoPdb Biochemical inhibition of recombinant PDE5A1 catalytic domain (aa535–860). - 6.43 pIC50 370 nM IC50 J Med Chem (2020) 63: 7867-7879 [PMID:32603117]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.