PF-07062119 [Ligand Id: 11125] activity data from GtoPdb
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Guanylyl cyclase-C in Monkey [GtoPdb: 1750] | ||||||||
| GtoPdb | Binding affinity for cynomolgus GUCY2C determined by SPR BIACore assay. | - | 8.52 | pKd | 3.01 | nM | Kd | Clin Cancer Res (2020) 26: 2188-2202 [PMID:31996389] |
| Guanylyl cyclase-C in Human [GtoPdb: 1750] [UniProtKB: P25092] | ||||||||
| GtoPdb | Binding affinity determined by SPR BIACore assay. | - | 8.13 | pKd | 7.47 | nM | Kd | Clin Cancer Res (2020) 26: 2188-2202 [PMID:31996389] |
| Guanylyl cyclase-C in Mouse [GtoPdb: 1750] [UniProtKB: Q3UWA6] | ||||||||
| GtoPdb | Binding affinity determined by SPR BIACore assay. | - | 7.76 | pKd | 17.27 | nM | Kd | Clin Cancer Res (2020) 26: 2188-2202 [PMID:31996389] |
| CD3e in Monkey [GtoPdb: 2742] | ||||||||
| GtoPdb | Binding affinity for cynomolgus CD3ε in a SPR BIACore assay. | - | 7.62 | pKd | 24.12 | nM | Kd | Clin Cancer Res (2020) 26: 2188-2202 [PMID:31996389] |
| CD3e in Human [GtoPdb: 2742] [UniProtKB: P07766] | ||||||||
| GtoPdb | Binding affinity for human CD3ε in a SPR BIACore assay. | - | 7.62 | pKd | 23.97 | nM | Kd | Clin Cancer Res (2020) 26: 2188-2202 [PMID:31996389] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
