BIIB068 [Ligand Id: 11178] activity data from GtoPdb

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  • Bruton tyrosine kinase in Human [GtoPdb: 1948] [UniProtKB: Q06187]
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  • Janus kinase 2 in Human [GtoPdb: 2048] [UniProtKB: O60674]
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  • mitogen-activated protein kinase kinase kinase 19 in Human [GtoPdb: 2076] [UniProtKB: Q56UN5]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Bruton tyrosine kinase in Human [GtoPdb: 1948] [UniProtKB: Q06187]
GtoPdb - - 9.52 pKd 0.3 nM Kd J. Med. Chem. (2020) : [PMID:32696648]
GtoPdb Biochemical assay measuring enzyme activity inhibition. - 9 pIC50 1 nM IC50 J. Med. Chem. (2020) : [PMID:32696648]
Janus kinase 2 in Human [GtoPdb: 2048] [UniProtKB: O60674]
GtoPdb - - 6.34 pKd 460 nM Kd J. Med. Chem. (2020) : [PMID:32696648]
mitogen-activated protein kinase kinase kinase 19 in Human [GtoPdb: 2076] [UniProtKB: Q56UN5]
GtoPdb - - 6.89 pKd 130 nM Kd J. Med. Chem. (2020) : [PMID:32696648]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.