vimseltinib [Ligand Id: 11190] activity data from GtoPdb

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  • platelet derived growth factor receptor alpha in Human [GtoPdb: 1803] [UniProtKB: P16234]
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  • KIT proto-oncogene, receptor tyrosine kinase in Human [GtoPdb: 1805] [UniProtKB: P10721]
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  • colony stimulating factor 1 receptor in Human [GtoPdb: 1806] [UniProtKB: P07333]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
platelet derived growth factor receptor alpha in Human [GtoPdb: 1803] [UniProtKB: P16234]
GtoPdb - - 6 pIC50 >1000 nM IC50 WO2014145025A2. 2-aminopyrimidin-6-ones and analogs exhibiting anti-cancer and anti-proliferative activities (2014)
KIT proto-oncogene, receptor tyrosine kinase in Human [GtoPdb: 1805] [UniProtKB: P10721]
GtoPdb - - 7 pIC50 100 nM IC50 WO2014145025A2. 2-aminopyrimidin-6-ones and analogs exhibiting anti-cancer and anti-proliferative activities (2014)
colony stimulating factor 1 receptor in Human [GtoPdb: 1806] [UniProtKB: P07333]
GtoPdb - - 8 pIC50 <10 nM IC50 WO2014145025A2. 2-aminopyrimidin-6-ones and analogs exhibiting anti-cancer and anti-proliferative activities (2014)

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.