ChEMBL ligand: CHEMBL3941880
FFA1 receptor/Free fatty acid receptor 1 in Human [ChEMBL: CHEMBL4422] [GtoPdb: 225] [UniProtKB: O14842] There should be some charts here, you may need to enable JavaScript!
FFA4 receptor/G-protein coupled receptor 120 in Human [ChEMBL: CHEMBL5339] [GtoPdb: 127] [UniProtKB: Q5NUL3] FFA4 receptor in Mouse [GtoPdb: 127] [UniProtKB: Q7TMA4] There should be some charts here, you may need to enable JavaScript!
FFA4 receptor in Human [GtoPdb: 127] [UniProtKB: Q5NUL3] FFA4 receptor/Omega-3 fatty acid receptor 1 in Mouse [ChEMBL: CHEMBL2052036] [GtoPdb: 127] [UniProtKB: Q7TMA4] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
FFA1 receptor/Free fatty acid receptor 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4422] [GtoPdb: 225] [UniProtKB: O14842]
ChEMBL	Antagonist activity against human FFA1 expressed in human Flp-In T-REx293 cells assessed as as reduction in TUG424-induced response by Fura2-AM dye based calcium mobilization assay	F	4	pIC50	>100000	nM	IC50	J Med Chem (2016) 59: 8868-8878 [PMID:27570890]
FFA4 receptor/G-protein coupled receptor 120 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5339] [GtoPdb: 127] [UniProtKB: Q5NUL3]
GtoPdb	Determined in a Ca2+ mobilization assay.	-	6.63	pEC50	234	nM	EC50	J Med Chem (2016) 59: 8868-8878 [PMID:27570890]
ChEMBL	Agonist activity at human FFA4 expressed in human Flp-In T-REx293 cells by Fura2-AM dye based calcium mobilization assay	F	6.63	pEC50	234.42	nM	EC50	J Med Chem (2016) 59: 8868-8878 [PMID:27570890]
ChEMBL	Agonist activity at C-terminal YFP-tagged human FFA4 expressed in HEK293 cells in presence of coelentrazine h by BRET based beta-arrestin-2 interaction assay	B	6.89	pEC50	128	nM	EC50	J Med Chem (2016) 59: 8868-8878 [PMID:27570890]
ChEMBL	Agonist activity at C-terminal YFP-tagged human FFA4 expressed in HEK293 cells in presence of coelentrazine h by BRET based beta-arrestin-2 interaction assay	B	6.91	pEC50	123.03	nM	EC50	J Med Chem (2016) 59: 8868-8878 [PMID:27570890]
FFA4 receptor in Mouse [GtoPdb: 127] [UniProtKB: Q7TMA4]
GtoPdb	Determined in a Ca2+ mobilization assay.	-	6.83	pEC50	148	nM	EC50	J Med Chem (2016) 59: 8868-8878 [PMID:27570890]
FFA4 receptor in Human [GtoPdb: 127] [UniProtKB: Q5NUL3]
GtoPdb	Determined in a Ca2+ mobilization assay.	-	6.63	pEC50	234	nM	EC50	J Med Chem (2016) 59: 8868-8878 [PMID:27570890]
FFA4 receptor/Omega-3 fatty acid receptor 1 in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2052036] [GtoPdb: 127] [UniProtKB: Q7TMA4]
ChEMBL	Agonist activity mouse FFA4 by by BRET based beta-arrestin-2 interaction assay	B	6.32	pEC50	478.63	nM	EC50	J Med Chem (2016) 59: 8868-8878 [PMID:27570890]
GtoPdb	Determined in a Ca2+ mobilization assay.	-	6.83	pEC50	148	nM	EC50	J Med Chem (2016) 59: 8868-8878 [PMID:27570890]
ChEMBL	Agonist activity mouse FFA4 by Gq-dependent calcium mobilization assay	F	6.83	pEC50	147.91	nM	EC50	J Med Chem (2016) 59: 8868-8878 [PMID:27570890]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]