taletrectinib [Ligand Id: 11198] activity data from GtoPdb

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  • neurotrophic receptor tyrosine kinase 1 in Human [GtoPdb: 1817] [UniProtKB: P04629]
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  • neurotrophic receptor tyrosine kinase 2 in Human [GtoPdb: 1818] [UniProtKB: Q16620]
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  • neurotrophic receptor tyrosine kinase 3 in Human [GtoPdb: 1819] [UniProtKB: Q16288]
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  • c-ros oncogene 1, receptor tyrosine kinase in Human [GtoPdb: 1840] [UniProtKB: P08922]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
neurotrophic receptor tyrosine kinase 1 in Human [GtoPdb: 1817] [UniProtKB: P04629]
GtoPdb - - 9.21 pIC50 0.62 nM IC50 Nat Commun (2019) 10: 3604 [PMID:31399568]
neurotrophic receptor tyrosine kinase 2 in Human [GtoPdb: 1818] [UniProtKB: Q16620]
GtoPdb - - 8.64 pIC50 2.28 nM IC50 Nat Commun (2019) 10: 3604 [PMID:31399568]
neurotrophic receptor tyrosine kinase 3 in Human [GtoPdb: 1819] [UniProtKB: Q16288]
GtoPdb - - 9.01 pIC50 0.98 nM IC50 Nat Commun (2019) 10: 3604 [PMID:31399568]
c-ros oncogene 1, receptor tyrosine kinase in Human [GtoPdb: 1840] [UniProtKB: P08922]
GtoPdb - - 9.7 pIC50 0.2 nM IC50 Nat Commun (2019) 10: 3604 [PMID:31399568]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.