Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
ChEMBL ligand: CHEMBL3137312 (ABT-333, Dasabuvir, Exviera) |
---|
There should be some charts here, you may need to enable JavaScript!
|
DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
---|---|---|---|---|---|---|---|---|
Hepatitis C virus NS5B RNA-dependent RNA polymerase in Hepatitis C virus (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5375] [UniProtKB: Q8JXU8] | ||||||||
ChEMBL | Inhibition of HCV genotype 1b NS5B RNA dependent RNA polymerase | B | 8.74 | pEC50 | 1.8 | nM | EC50 | MedChemComm (2019) 10: 991-1006 |
ChEMBL data shown on this page come from version 28:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]