bemarituzumab [Ligand Id: 11278] activity data from GtoPdb

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  • fibroblast growth factor receptor 2 in Human [GtoPdb: 1809] [UniProtKB: P21802]
  • This target only has 0 pki data point
  • 0
1 _lig_chart_1 fibroblast growth factor receptor 2 Human
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  • Fc fragment of IgG receptor IIIa in Human [GtoPdb: 3017] [UniProtKB: P08637]
  • This target only has 0 pki data point
  • 0
2 _lig_chart_2 Fc fragment of IgG receptor IIIa Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
fibroblast growth factor receptor 2 in Human [GtoPdb: 1809] [UniProtKB: P21802]
GtoPdb Binding affinity to FGFR2a ECD by SPR. - 9.24 pKd 0.58 nM Kd Cancer Chemother Pharmacol (2020) 86: 595-606 [PMID:32965540]
Fc fragment of IgG receptor IIIa in Human [GtoPdb: 3017] [UniProtKB: P08637]
GtoPdb Binding affinity of FcγRIIIa (V158) for immobilised antibody by SPR. - 8.04 pKd 9.2 nM Kd Cancer Chemother Pharmacol (2020) 86: 595-606 [PMID:32965540]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.