ChEMBL ligand: CHEMBL267865
Cyclooxygenase-2 in Sheep [ChEMBL: CHEMBL4102] [UniProtKB: P79208] There should be some charts here, you may need to enable JavaScript!
CYP2C19/Cytochrome P450 2C19 in Human [ChEMBL: CHEMBL3622] [GtoPdb: 1328] [UniProtKB: P33261] There should be some charts here, you may need to enable JavaScript!
CYP4F12 in Human [GtoPdb: 1348] [UniProtKB: Q9HCS2] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Cyclooxygenase-2 in Sheep (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4102] [UniProtKB: P79208]
ChEMBL	Tested for inhibitory activity against Prostaglandin G/H synthase	B	5.64	pIC50	2300	nM	IC50	Bioorg Med Chem Lett (2001) 11: 2993-2995 [PMID:11714595]
CYP2C19/Cytochrome P450 2C19 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3622] [GtoPdb: 1328] [UniProtKB: P33261]
ChEMBL	Inhibition of cytochrome P450 CYP2C19	B	6.57	pIC50	272	nM	IC50	J Med Chem (2003) 46: 5416-5427 [PMID:14640550]
CYP4F12 in Human [GtoPdb: 1348] [UniProtKB: Q9HCS2]
GtoPdb	-	-	7.86	pIC50	13.7	nM	IC50	J Pharmacol Exp Ther (2018) 366: 446-457 [PMID:29976573]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]