elraglusib [Ligand Id: 11412] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL483465 (9-ing-41)
  • glycogen synthase kinase 3 beta/Glycogen synthase kinase-3 beta in Human [ChEMBL: CHEMBL262] [GtoPdb: 2030] [UniProtKB: P49841]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
glycogen synthase kinase 3 beta/Glycogen synthase kinase-3 beta in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL262] [GtoPdb: 2030] [UniProtKB: P49841]
ChEMBL Inhibition of human GSK3-beta by scintillation counting B 6.15 pIC50 710 nM IC50 J. Med. Chem. (2009) 52: 1853-1863 [PMID:19338355]
GtoPdb Measuring inhibition of GSK-3β-mediated phosphorylation of a peptide substrate in vitro. - 6.15 pIC50 710 nM IC50 J Med Chem (2009) 52: 1853-63 [PMID:19338355]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]