ChEMBL ligand: CHEMBL13608 (Palladia, PHA-291639, Toceranib)
epidermal growth factor receptor/Epidermal growth factor receptor erbB1 in Human [ChEMBL: CHEMBL203] [GtoPdb: 1797] [UniProtKB: P00533] There should be some charts here, you may need to enable JavaScript!
fibroblast growth factor receptor 1/Fibroblast growth factor receptor 1 in Human [ChEMBL: CHEMBL3650] [GtoPdb: 1808] [UniProtKB: P11362] There should be some charts here, you may need to enable JavaScript!
platelet derived growth factor receptor beta/platelet derived growth factor receptor alpha in Human [GtoPdb: 1804, 1803] [UniProtKB: P09619, P16234] platelet derived growth factor receptor beta/platelet derived growth factor receptor alpha/Platelet-derived growth factor receptor in Mouse [ChEMBL: CHEMBL2096980] [GtoPdb: 1804, 1803] [UniProtKB: P05622, P26618] There should be some charts here, you may need to enable JavaScript!
platelet derived growth factor receptor beta/Platelet-derived growth factor receptor beta in Human [ChEMBL: CHEMBL1913] [GtoPdb: 1804] [UniProtKB: P09619] There should be some charts here, you may need to enable JavaScript!
kinase insert domain receptor/Vascular endothelial growth factor receptor 2 in Human [ChEMBL: CHEMBL279] [GtoPdb: 1813] [UniProtKB: P35968] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
epidermal growth factor receptor/Epidermal growth factor receptor erbB1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL203] [GtoPdb: 1797] [UniProtKB: P00533]
ChEMBL	Inhibition of epidermal growth factor receptor (EGF-R)	B	4.7	pIC50	>20000	nM	IC50	J Med Chem (2003) 46: 1116-1119 [PMID:12646019]
fibroblast growth factor receptor 1/Fibroblast growth factor receptor 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3650] [GtoPdb: 1808] [UniProtKB: P11362]
GtoPdb	-	-	6.3	pKi	500	nM	Ki	Blood (2002) 100: 585-93 [PMID:12091352]
ChEMBL	Inhibition of Fibroblast growth factor receptor 1	B	5.41	pIC50	3900	nM	IC50	J Med Chem (2003) 46: 1116-1119 [PMID:12646019]
platelet derived growth factor receptor beta/platelet derived growth factor receptor alpha in Human [GtoPdb: 1804, 1803] [UniProtKB: P09619, P16234]
GtoPdb	-	-	8.3	pKi	5	nM	Ki	Blood (2002) 100: 585-93 [PMID:12091352]
platelet derived growth factor receptor beta/platelet derived growth factor receptor alpha/Platelet-derived growth factor receptor in Mouse (target type: PROTEIN COMPLEX) [ChEMBL: CHEMBL2096980] [GtoPdb: 1804, 1803] [UniProtKB: P05622, P26618]
ChEMBL	Inhibition of Platelet-derived growth factor induced 3T3 cell proliferation	F	7	pIC50	100	nM	IC50	J Med Chem (2003) 46: 1116-1119 [PMID:12646019]
ChEMBL	Inhibition of PDGF-induced BrdU incorporation in 3T3 cells	F	7.15	pIC50	<70	nM	IC50	J Med Chem (2003) 46: 1116-1119 [PMID:12646019]
platelet derived growth factor receptor beta/Platelet-derived growth factor receptor beta in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1913] [GtoPdb: 1804] [UniProtKB: P09619]
ChEMBL	Inhibition of Platelet-derived growth factor receptor beta (PDGF-Rbeta)	B	9	pIC50	1	nM	IC50	J Med Chem (2003) 46: 1116-1119 [PMID:12646019]
kinase insert domain receptor/Vascular endothelial growth factor receptor 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL279] [GtoPdb: 1813] [UniProtKB: P35968]
GtoPdb	-	-	8.22	pKi	6	nM	Ki	Blood (2002) 100: 585-93 [PMID:12091352]
ChEMBL	Inhibition of Vascular endothelial growth factor receptor 2	B	7.22	pIC50	60	nM	IC50	J Med Chem (2003) 46: 1116-1119 [PMID:12646019]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]