XMD-12 [Ligand Id: 11665] activity data from GtoPdb

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  • aurora kinase A in Human [GtoPdb: 1936] [UniProtKB: O14965]
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  • aurora kinase B in Human [GtoPdb: 1937] [UniProtKB: Q96GD4]
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  • leucine rich repeat kinase 2 in Human [GtoPdb: 2059] [UniProtKB: Q5S007]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
aurora kinase A in Human [GtoPdb: 1936] [UniProtKB: O14965]
GtoPdb - - 8.25 pIC50 5.6 nM IC50 ACS Chem Biol (2012) 7: 185-96 [PMID:21992004]
aurora kinase B in Human [GtoPdb: 1937] [UniProtKB: Q96GD4]
GtoPdb - - 7.74 pIC50 18.4 nM IC50 ACS Chem Biol (2012) 7: 185-96 [PMID:21992004]
leucine rich repeat kinase 2 in Human [GtoPdb: 2059] [UniProtKB: Q5S007]
GtoPdb - - 7.52 pIC50 30 nM IC50 ACS Chem Biol (2012) 7: 185-96 [PMID:21992004]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.