sunvozertinib [Ligand Id: 11672] activity data from GtoPdb

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  • epidermal growth factor receptor in Human [GtoPdb: 1797] [UniProtKB: P00533]
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  • Bruton tyrosine kinase in Human [GtoPdb: 1948] [UniProtKB: Q06187]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
epidermal growth factor receptor in Human [GtoPdb: 1797] [UniProtKB: P00533]
GtoPdb Inhibition of WT EGFR phosphorylation in A431 cells - 7.09 pIC50 80.4 nM IC50 WO2019149164A1. Erbb/btk inhibitors (2019)
Bruton tyrosine kinase in Human [GtoPdb: 1948] [UniProtKB: Q06187]
GtoPdb Inhibition of BTK phosphorylation in Ramos cells (B lymphocyte cell line) - 8.54 pIC50 2.9 nM IC50 WO2019149164A1. Erbb/btk inhibitors (2019)

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.