Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
ChEMBL ligand: CHEMBL88240 (Alniditan) |
---|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
---|---|---|---|---|---|---|---|---|
5-HT1A receptor/Serotonin 1a (5-HT1a) receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL214] [GtoPdb: 1] [UniProtKB: P08908] | ||||||||
ChEMBL | Ability to bind to 5-hydroxytryptamine 1A receptor from cloned human expressed in Ha7 cells | B | 8.3 | pIC50 | 5.01 | nM | IC50 | Bioorg. Med. Chem. Lett. (1995) 5: 2649-2654 |
5-HT1D receptor/Serotonin 1d (5-HT1d) receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1983] [GtoPdb: 3] [UniProtKB: P28221] | ||||||||
GtoPdb | - | - | 8.92 | pKd | 1.2 | nM | Kd | Br J Pharmacol (1998) 123: 1655-65 [PMID:9605573] |
ChEMBL | Ability to bind to 5-hydroxytryptamine 1D receptor of calf substantia nigra | B | 8.6 | pIC50 | 2.51 | nM | IC50 | Bioorg. Med. Chem. Lett. (1995) 5: 2649-2654 |
5-HT1B receptor in Human [GtoPdb: 2] [UniProtKB: P28222] | ||||||||
GtoPdb | - | - | 9 | pKd | 1 | nM | Kd | Br J Pharmacol (1998) 123: 1655-65 [PMID:9605573] |
ChEMBL data shown on this page come from version 31:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]