tegoprazan [Ligand Id: 12008] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL4297583 (Lxi-15028, LXI-15028, Tegoprazan)
  • ATP4A in Human [GtoPdb: 849] [UniProtKB: P20648]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
ATP4A in Human [GtoPdb: 849] [UniProtKB: P20648]
GtoPdb Inhibition of the H+/K+-ATPase activity of recombinant human enzyme - 6.28 pIC50 520 nM IC50 J Pharmacol Exp Ther (2018) 364: 275-286 [PMID:29180359]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]