ChEMBL ligand: CHEMBL288474
integrin, beta 1 subunit (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)/integrin, alpha 4 subunit (antigen CD49D, alpha 4 subunit of VLA-4 receptor)/Integrin alpha-4/beta-1 in Human [ChEMBL: CHEMBL1907599] [GtoPdb: 2455, 2443] [UniProtKB: P05556, P13612] There should be some charts here, you may need to enable JavaScript!
integrin, alpha 4 subunit (antigen CD49D, alpha 4 subunit of VLA-4 receptor)/integrin, beta 7 subunit/Integrin alpha-4/beta-7 in Human [ChEMBL: CHEMBL2095184] [GtoPdb: 2443, 2461] [UniProtKB: P13612, P26010] There should be some charts here, you may need to enable JavaScript!
integrin, alpha 9 subunit in Human [GtoPdb: 2448] [UniProtKB: Q13797] There should be some charts here, you may need to enable JavaScript!
integrin α4β1 in Human [GtoPdb: 2580] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
integrin, beta 1 subunit (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)/integrin, alpha 4 subunit (antigen CD49D, alpha 4 subunit of VLA-4 receptor)/Integrin alpha-4/beta-1 in Human (target type: PROTEIN COMPLEX) [ChEMBL: CHEMBL1907599] [GtoPdb: 2455, 2443] [UniProtKB: P05556, P13612]
ChEMBL	Alpha4-beta1 integrin binding affinity was assessed by measuring the reduction in binding of [125I]VCAM-Ig to a suspension of Jurkat cells (a human T cell line alpha-4-beta-1-beta-7)	B	9.85	pIC50	0.14	nM	IC50	Bioorg Med Chem Lett (2002) 12: 159-163 [PMID:11755344]
integrin, alpha 4 subunit (antigen CD49D, alpha 4 subunit of VLA-4 receptor)/integrin, beta 7 subunit/Integrin alpha-4/beta-7 in Human (target type: PROTEIN COMPLEX) [ChEMBL: CHEMBL2095184] [GtoPdb: 2443, 2461] [UniProtKB: P13612, P26010]
ChEMBL	Alpha4-beta7 integrin binding affinity was determined in duplicate by a radioligand binding assay using [125I]-VCAM-Ig and a suspension of RPMI-8866 cells (a human B cell line alpha-4-beta-1-beta-7+)	B	8.55	pIC50	2.83	nM	IC50	Bioorg Med Chem Lett (2002) 12: 159-163 [PMID:11755344]
integrin, alpha 9 subunit in Human [GtoPdb: 2448] [UniProtKB: Q13797]
GtoPdb	Binding affinity for α9β1 intergrin in vitro	-	11.52	pKd	0	nM	Kd	Biochemistry (2002) 41: 7125-41 [PMID:12033947]
integrin α4β1 in Human [GtoPdb: 2580]
GtoPdb	-	-	11.3	pKd	0	nM	Kd	Biochemistry (2002) 41: 7125-41 [PMID:12033947]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]