compound 33a [PMID: 35944901] [Ligand Id: 12126] activity data from GtoPdb

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  • ABL proto-oncogene 1, non-receptor tyrosine kinase in Human [GtoPdb: 1923] [UniProtKB: P00519]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
ABL proto-oncogene 1, non-receptor tyrosine kinase in Human [GtoPdb: 1923] [UniProtKB: P00519]
GtoPdb Inhibition of BCR-AblT315I - 7.36 pIC50 43.7 nM IC50 J Med Chem (2022) 65: 10898-10919 [PMID:35944901]
GtoPdb Inhibition of WT BCR-Abl - 7.7 pIC50 20.1 nM IC50 J Med Chem (2022) 65: 10898-10919 [PMID:35944901]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.