BI-4142 [Ligand Id: 12164] activity data from GtoPdb
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| epidermal growth factor receptor in Human [GtoPdb: 1797] [UniProtKB: P00533] | ||||||||
| GtoPdb | Inhibition of autophosphorylation of WT EGFR overexpressed in HEK293 cells | - | 6.57 | pIC50 | 270 | nM | IC50 | Nat Cancer (2022) 3: 821-836 [PMID:35883003] |
| erb-b2 receptor tyrosine kinase 2 in Human [GtoPdb: 2019] [UniProtKB: P04626] | ||||||||
| GtoPdb | Cellular assay: inhibition of proliferation of NCI-H2170 cells expressing HER2YVMA | - | 7.09 | pIC50 | 82 | nM | IC50 | Nat Cancer (2022) 3: 821-836 [PMID:35883003] |
| GtoPdb | Inhibition of auto-phosphorylation of HER2YVMA overexpressed in HEK293 cells | - | 8 | pIC50 | 10 | nM | IC50 | Nat Cancer (2022) 3: 821-836 [PMID:35883003] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
