D5261 [Ligand Id: 12213] activity data from GtoPdb

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  • neurotrophic receptor tyrosine kinase 1 in Human [GtoPdb: 1817] [UniProtKB: P04629]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
neurotrophic receptor tyrosine kinase 1 in Human [GtoPdb: 1817] [UniProtKB: P04629]
GtoPdb Inhibition of TrkA activity in Ba/F3-MPRIP-TrkA cells. - 5.48 pIC50 3320 nM IC50 Eur J Med Chem (2022) 228: 114022 [PMID:34871843]
GtoPdb Antiproliferative activity against Ba/F3-CD74-TrkA cells. - 5.54 pIC50 2910 nM IC50 Eur J Med Chem (2022) 228: 114022 [PMID:34871843]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.