EGFR inhibitor 57 [Ligand Id: 12278] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| epidermal growth factor receptor in Human [GtoPdb: 1797] [UniProtKB: P00533] | ||||||||
| GtoPdb | Inhibition potency for EGFR with the L858R/C797S double mutation | - | 7.7 | pIC50 | 20 | nM | IC50 | J Med Chem (2022) 65: 13052-13073 [PMID:36178776] |
| GtoPdb | Inhibition potency for EGFR with the L858R/T790M/C797S triple mutation. | - | 8.7 | pIC50 | 2 | nM | IC50 | J Med Chem (2022) 65: 13052-13073 [PMID:36178776] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
