ranitidine [Ligand Id: 1234] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL512
  • H2 receptor in Human [GtoPdb: 263] [UniProtKB: P25021]
  • H2 receptor in Rat [GtoPdb: 263] [UniProtKB: P25102]
1 CHEMBL512_lig_chart_1 H2 receptor HumanRat
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
H2 receptor in Human [GtoPdb: 263] [UniProtKB: P25021]
GtoPdb - - 7.1 pKi 79.4 nM Ki Br. J. Pharmacol. (1994) 112: 847-54 [PMID:7921611]
H2 receptor in Rat [GtoPdb: 263] [UniProtKB: P25102]
GtoPdb - - 6.2 pKi 631 nM Ki Br. J. Pharmacol. (1997) 122: 867-74 [PMID:9384502]

ChEMBL data shown on this page come from version 27:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]