sabatolimab [Ligand Id: 12361] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| TIM3 (CD366) in Monkey [GtoPdb: 2940] | ||||||||
| GtoPdb | Binding affinity for recombinant cyno TIM3 by BiaCore analysis | - | 9.14 | pKd | 0.72 | nM | Kd | Immunother Adv (2022) 2: ltac019 [PMID:36196369] |
| TIM3 (CD366) in Human [GtoPdb: 2940] [UniProtKB: Q8TDQ0] | ||||||||
| GtoPdb | Binding affinity for recombinant hTIM3 by BiaCore analysis | - | 9.78 | pKd | 0.17 | nM | Kd | Immunother Adv (2022) 2: ltac019 [PMID:36196369] |
| GtoPdb | Inhibition of galectin-9 binding to hTIM3 using a MesoScale discovery platform with plate-bound TIM3 and Sulfo-Tagged galectin-9 as substrate | - | 8.32 | pIC50 | 4.74 | nM | IC50 | Immunother Adv (2022) 2: ltac019 [PMID:36196369] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
