risvodetinib [Ligand Id: 12383] activity data from GtoPdb

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  • KIT proto-oncogene, receptor tyrosine kinase in Human [GtoPdb: 1805] [UniProtKB: P10721]
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  • ABL proto-oncogene 1, non-receptor tyrosine kinase in Human [GtoPdb: 1923] [UniProtKB: P00519]
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  • ABL proto-oncogene 2, non-receptor tyrosine kinase in Human [GtoPdb: 1924] [UniProtKB: P42684]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
KIT proto-oncogene, receptor tyrosine kinase in Human [GtoPdb: 1805] [UniProtKB: P10721]
GtoPdb - - 8.11 pIC50 7.8 nM IC50 US20200046699A1. Compositions and methods for inhibiting kinases (2020)
ABL proto-oncogene 1, non-receptor tyrosine kinase in Human [GtoPdb: 1923] [UniProtKB: P00519]
GtoPdb - - 7.33 pIC50 47 nM IC50 US20200046699A1. Compositions and methods for inhibiting kinases (2020)
ABL proto-oncogene 2, non-receptor tyrosine kinase in Human [GtoPdb: 1924] [UniProtKB: P42684]
GtoPdb - - 7.11 pIC50 77 nM IC50 US20200046699A1. Compositions and methods for inhibiting kinases (2020)

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.