cyclamate [Ligand Id: 12470] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1206440 (Cyclamate, Cyclamic acid, E-952(I), Hexamic acid, INS-952(I), INS NO.952(I), NSC-220327)
  • TAS2R31 in Human [GtoPdb: 674] [UniProtKB: P59538]
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  • TAS2R43 in Human [GtoPdb: 678] [UniProtKB: P59537]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
TAS2R31 in Human [GtoPdb: 674] [UniProtKB: P59538]
GtoPdb - - 1.79 pIC50 16200000 nM IC50 Cell Chem Biol (2017) 24: 1199-1204.e2 [PMID:28919036]
TAS2R43 in Human [GtoPdb: 678] [UniProtKB: P59537]
GtoPdb - - 2.32 pIC50 4800000 nM IC50 Cell Chem Biol (2017) 24: 1199-1204.e2 [PMID:28919036]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]