dosimertinib [Ligand Id: 12710] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| epidermal growth factor receptor in Human [GtoPdb: 1797] [UniProtKB: P00533] | ||||||||
| GtoPdb | Enzymatic inhibitory activity vs. WT EGFR | - | 6.94 | pIC50 | 113.8 | nM | IC50 | J Med Chem (2021) 64: 925-937 [PMID:33459024] |
| GtoPdb | Enzymatic inhibitory activity vs. L858R/T790M EGFR | - | 8.77 | pIC50 | 1.7 | nM | IC50 | J Med Chem (2021) 64: 925-937 [PMID:33459024] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
